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0 Comment February 7, 2017

Fen Phen cosmetic surgery complication

Obesity is known to be the number one public health problem in America. In some states, up to 40% of the adult population is obese. As a result, various medical options have been studied for decades. Two of these medications utilized for weight reduction are fenfluramine and phentermine, which together make up the famous fen-phen.

Fenfluramine is also known as sympathomimetic. This means that this medication affects the sympathetic systems that control many aspects of your body. It increases serotonin and also glucose utilization. On the other hand, Phentermine is an appetite suppressant similar to amphetamine. Though it is also a sympathomimetic medication, Phentermine stimulates the hypothalamus, which decreases appetite, and significantly reduces hunger and food intake in overweight individuals. Compared to fenfluramine, Phentermine is more of a stimulant. With these results, fen-phen can increase heart rate and pulmonary arterial pressure as well as overall body blood pressure. Though there are benefits that you could get with fen-phen, you need to take into consideration that there are numerous reasons why it is not a good idea to be on this medication before having a cosmetic surgery.

When put under anesthesia, patients who have taken fen-phen can develop persistent or prolonged hypotension or low blood pressure that is unresponsive to medications like ephedrine. Thus, it creates a problem for the anesthesiologist because the patient can actually die even if the low blood pressure is treated with medication used to increase blood pressure. In addition, fen-phen can cause the stomach to empty too slowly, which can lead to aspiration during or after surgery. If you are diabetic, fenfluramine can increase the insulin effect by increasing the uptake of glucose and decreasing the liver production of glucose, which makes it problematic to monitor your blood sugar during surgery. Before you take the fen-phen, be reminded that there are anesthetic systemic effects related to it.


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