Fat transfer to the buttocks provides natural, effective, and long-lasting outcomes. However, for the results to remain with you in the long run, you need to maintain a stable weight. Drastic weight loss after the intervention can affect the achieved results in negative ways. When the excess fat is removed from different areas of your body and injected into the buttocks, your body starts treating the transferred fat just like the fat in other areas of your body. After transferring the fat to the buttocks, your body gradually vascularizes the fat cells, meaning that it establishes blood flow to them. This helps the fat cells survive and behave just like the fat in other parts of the body. As a result of this phenomenon, drastic weight loss will affect your buttocks in the same way as it does in other areas of the body. Substantial weight loss will shrink the fat cells because nutrients will not be available to them. In the case of extreme weight loss, some of the fat cells may even die. When the fat cells in your buttocks shrink, it causes the buttocks to decrease in size and lose the achieved shape to some extent. On the other hand, weight gain will do the opposite. It will lead to growth and expansion of the fat cells and may even trigger the birth of new fat cells. After the fat transfer to the buttocks, you must stick to a stable weight to maintain the achieved results. You should be sure to eat a healthy and balanced diet. Doing so will make the outcomes of the intervention permanent, and you will not need any touch-up fat injections in the future. If you have already experienced drastic weight loss after fat transfer to the buttocks and the shape and volume of your buttocks have changed, you should gain weight. This will help the fat cells expand again. The best way to avoid change in your butt size or contour after the fat transfer is to maintain a balanced weight from the start.